Also too much insulin inhibits production of ketones and insulin inhibits lipolysis and ketogenesis and stimulates lipogenesis. Due to how easily it would be to fall out of dietary ketogenic, thus out of ketosis by eating just enough carbs in just one day to exceed the limit, wouldnt it make sense to check daily their BHB ketone levels? I say this because its possible someone who is on daily insulin can still be taking more insulin than is required while they unknowingly just switched back to a glucose adapted energy state. Now this person of course has reduced their insulin levels significantly and changed their macronutrients to consume 30g carbs (10%), 70% fat and 20 % protein. JDM, Ronpfid, Mark Munday, or AnnC, lets say someone who is a T1 and just starting out on a ketogenic diet who then verifies their in nutritional ketosis by measuring their blood BHB to see that their ketone body level is between 0.5 and 3.0. Most of the problematic fat was made from excess glucose, anyway. Fasting and even extremely low-fat eating can help this in the short run but IMO are not healthy long-term solutions. With glucose incoming every few waking hours and insulin rarely if ever reaching baseline, fat metabolism is very suppressed resulting in, among other things, higher circulating fats like triglycerides (which reside in lipoproteins) and FFAs. So, most modern diet eaters, in addition to never seeing a whiff of ketones also have severely compromised fat metabolism. Furthermore, the presence of insulin suppresses metabolism of fat. Ketones can be used by all cells in the body - at least all cells that use insulin for glucose uptake or have anything to do with IR.Įveryone probably burns at least little fat for energy, although anyone on a "normal" modern diet won't have any ketones around. In the more specific state of ketosis, some of the available fat is metabolized in the liver to produce ketones. Muscles and other cells can do this directly as FFAs, not ketones, but not all cells can do that. FFAs are always released from adipose for use as energy. Yes, those were meant as two different things, "in circulation" (FFAs) and "from stores" (released from adipose and de-esterified - lipolysis). I'm just trying to maintain and benefit from my metabolism's preference for fat/ketones for energy over glucose. ![]() I'm not losing weight nor trying to lose weight. The presence of some glucose and insulin does nothing good and just confuses the situation. There are fats in circulation and they can be mobilized fast enough from stores. In other words, the fuel needed for non-extreme exertion is already there in the fat-adapted metabolism whether you eat or not. So, if your NORMAL is burning fat for energy with the exception of very extreme exertion like power-lifting (which I don't do), the situation is quite different than a metabolism which ONLY switches to significant fat-over-glucose energy with extreme prodding. I'm not convinced that's a good idea at all and don't think it fits my lifestyle. I think some exercise enthusiasts think that's a good idea - drain muscle glycogen (and probably liver, too) and the replace it at the next carb-loading. ![]() First and foremost, it will utilize glycogen and for muscle action, that includes the one stored in muscle. If it is no forthcoming from digestion, it has other tricks. Remember, this metabolism is quite insistent on glucose. ![]() In that context, I think everything you said makes sense. Aside from over-simplification, I think you're talking exactly about the glucocentric metabolism.
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